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Saturday, June 30, 2012
Euro deal leaves deep divisions, questions
Markus Schreiber / AP
German Chancellor Angela Merkel addresses lawmakers on the decisions of the EU summit at the parliament Bundestag in Berlin Friday, June 29. Chancellor Merkel faces a vote on the eurozone's new permanent rescue fund and the EU's fiscal co-pact. Merkel is reflected in the windows of a visitors balcony at the plenary hall.
By John W. Schoen, Senior Producer
A "breakthrough" agreement by European leaders?desperate to show the world they haven?t run out of ideas to save the eurozone?is short on details and does little more than buy time, analysts said Friday.
And after 21 summit meetings convened to?head off the looming breakup of Europe?s common currency and the continent's ongoing downward economic spiral, it is not clear how much time the deal?to shore up wobbly banks will buy.
?Every time they come out with something, it seems to lasts an increasingly smaller amount of time,? said Guy Wolf, a market strategist at commodities broker Marex Specton in London. ?I don't see anything in this current statement that makes me think someone will go and build a factory in Spain. And that's what we're really talking about.?
With Greece?s economy in ruins, Spain?s banks on life support and Italy?s borrowing costs rising, eurozone leaders broke out the fire hoses at their latest meeting in Brussels.
The new measures, hammered out after 14 hours of contentious talks that pitted Rome and Madrid against Europe's paymaster Berlin, amounted to a willingness to bend the European Union?s existing aid rules to shore up failing banks and try to bring down rising borrowing costs that are strangling the weaker?economies.
Under the latest plan, Europe?s two bailout funds will be allowed to buy bank shares directly instead of channeling the money through member governments. But the agreement included little detail on just how the new measures would be implemented.
It?s not clear, for example, who will decide which banks get funds, how much they?ll get or what conditions will be imposed in return for bailouts. Failed banks would be taken over by the European Central Bank, which currently has no system in place to do so.
With expectations for the summit so low, ?financial markets staged a ?relief? rally after the deal was announced. The euro rose sharply against the dollar and yields on Spanish and Italian debt fell sharply. The Dow Jones industrial average was up more than 220 points in midday trading.
?We have avoided an Armageddon scenario ? at least for the summer,? said Tai Hui, chief economist at?Standard Chartered?Bank.
But the agreement does little to bridge the widening political and economic divisions that continue to threaten Europe?s common currency and economic future.
The summit was supposed to have addressed Greece?s urgent need for assistance. Leaders of the newly formed Athens government, facing insolvency within weeks, have vowed to roll back German-imposed austerity measures that were agreed to by the former Athens government in return for aid.
A volatile confrontation between Athens and Berlin was averted when Greece?s new prime minister last week cancelled his trip for health reasons, and the newly appointed finance minister was replaced, also for health reasons. The long-running standoff between Greece and Germany remains unresolved. ?
With Greece off the agenda, attention at the two-day Brussels summit turned to the more imminent crisis in Spain, which recently asked for a bank bailout that could reach 100 billion euros ($125 billion).?
Some economists believe the bank bailout may be a preamble to a wider bailout of the Spanish government, which has recently seen its credit ratings slashed and borrowing costs rise to unsustainable levels.?While some economists and eurozone officials believe the impact of Greece's departure from the common currency could be managed, Spain's much-larger economy and pool of outstanding debt poses a greater risk. ??
The fallout from Spain has also pushed up borrowing costs for the Italian government, Europe?s third-largest economy and most heavily indebted eurozone country.
Friday?s summit agreement was aimed at calming investors who have been fleeing Spanish banks and government bonds. But it remains to be seen how much investor confidence the proposed bank backstop measures can restore in Spanish and Italian government bonds.
?There are a number of uncertainties about the conditions applied to (the backstop) and the rating agency?s reaction to countries applying for outside help,? said Philippe Bodereau, head of European credit research at PIMCO.
The summit brought into sharper focus the deepening divisions among European leaders, as Germany increasingly finds itself cast in the role of Europe?s financial guarantor. As the Europe?s largest economy enjoys relative prosperity ? thanks in part to massive capital flight into German banks and government bonds ? German voters have grown increasingly wary of further calls to commit their hard-earned savings to bail out their neighbors. ?
Following this week's summit, some reports suggested that German Chancellor Angela Merkel appeared to soften her steadfast opposition to guaranteeing other country?s debts. But with voter resistance to the idea running high back home, Germany?s leaders can ill-afford to?commit?to paying the bills of other euro zone governments.
?Germany has no good options,? said Wolf. ?They either pay an incredibly large bill when the euro area breaks up or sign themselves up to a perpetual series of transfers to the rest of the euro area. So it's not surprising that they are stalling that decision for as long as possible. Because no politician wants to be saddled with that answer.?
CNBC's Michelle Caruso-Cabrera reports the latest details on the agreement reached at the EU Summit.
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Friday, June 29, 2012
Syrian opposition rejects Annan plan if Assad stays
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Source: http://news.yahoo.com/syrian-opposition-rejects-annan-plan-assad-stays-083733136.html
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Air Force says 31 victims so far in sex scandal
WASHINGTON (AP) ? A senior Air Force commander says 31 female victims have been identified so far in a widening sex scandal that has rocked the service's training command at Lackland Air Force Base in Texas.
Gen. Edward Rice, commander of the Air Education and Training Command, tells Pentagon reporters that a dozen male instructors are under investigation, and that nine of them are from the same unit ? the 331st Training Squadron.
Rice says the Air Force believes this is not a problem endemic to the nine training squadrons, and that it appears to be localized. He says the sexual misconduct occurred over the past two and one-half years, but the first woman came forward only a year ago.
The Air Force has launched an independent investigation across all training units.
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Google releases Chrome browser for iPhone, iPad
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Source: http://news.yahoo.com/google-releases-chrome-browser-iphone-ipad-175436415.html
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Thursday, June 28, 2012
Learn How To Run Small Business Internet Marketing |
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Wednesday, June 27, 2012
Online Car Rental | Oregon Attractions
You will not deny the fact that commuting in a place that is new to you is very difficult and sometimes impossible. You always need a good travel agency as well as a car hired from reliable car rentals. The only difficulty that arises is to find the right place to hire the car. Finding a discount car rental deals will not happen in a minute but will take much of your time. First, you will need to pay a visit to many rental providers in order to know the best rates. And you will conclude this by comparing the rates of different service providers. It is must that you go for the best deal if you want to spend your summer vacations rightly. To start your work, look for the rates of top agencies which include Avis, Budget, Hertz and Enterprise online. Look for discount offers and other seasonal special offers provided by these companies.
From a number of websites offering information online car rental, you can easily find rental properties online. All you have to do is to pick them up which you?ll find plenty in minutes. The correct way is to browse a few pages and then look for the rates it is offering at the place from where you can rent a car. To compare the prices offered by different websites, you should write down and compare them. Many sites are connected with many car rental companies. These pages are a best way to find a car that is easy and affordable. Car rental deals are also provided by many online travel agencies.
Facilities of car rentals are provided by many online travel agencies. These agencies help you to save your time by negotiating with the providers themselves to offer their travellers competitive prices. Therefore, it is best to book car rentals online to make your travelling comfortable. These sites and agencies will surely prove to be advantageous. Agencies are no doubt a perfect option to find the deal which is best among all others.
To hire a car online, all you need to do is enter the place, date and car specifications. This will show you a list of car rental services with their details mentioned. Details include model of car, type, accommodation and price. These sites also provide special discount to their customers and hence, are the best place to get car rental deals. One such site is MyTravelAsia.com. The site is wholly dedicated to tour planning and bookings and is a best place to get discounts.
Don?t let your summer trip or tour get ruined by hiring an inefficient car rental. Your money and time are precious and not to be spent on any cheap service provider. You can get help from online resources which will let you find a deal that is suitable in terms of budget and efficiency. Apart from saving your money and time, these sites also provide you a deal that are the best among all other car rental deals. Spend your money wisely if you want to spend vacations to the fullest.
Are you looking for car rental cheap information? Always lok for some relible resource for cheap rental cars
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Tips to Buy Your Mobile Phones and Pda Accessories - lovelytwitz
Among all the electronic gadgets that have hogged popular attention around the world, mobile phones and PDAs (Personal Digital Assistant) are more ubiquitous and popular these days. While mobile phones have made communication fast and easy, PDAs have ensured busy executives stay connected to information, clients and social networks on the move. Not surprisingly, the widespread use of these hand-held gadgets has triggered an increasing need for accessories as well. For instance, these days, mobile phones accessories and PDA accessories have become extremely essential for virtually every individual who owns a mobile phone or PDA.
According to surveys, over 80% of the mobile phone and cell phone users express their strong desire to buy some kind of cell phones accessories or PDA accessories or other for to complement their handheld gadgets. While phone accessories such as mobile phones dock, mobile phones stand, memory cards, mobile phone batteries and mobile opening tools are in huge demand in the electronics consumer market, all sorts of PDA accessories ranging from PDA Batteries, PDA Car Accessories, PDA Cases, PDA Chargers and PDA Display Protects are among the top Internet searches by gadget-savvy consumers in the UK.
When it comes to mobile phones and PDA accessories, many people find Internet to be the best place to find what they want. A large percentage of consumers visit popular ecommerce websites in search of their mobile phones accessories, PDA accessories, and other gadget related accessories. Quite a few reasons are responsible why such a large number of people turn to popular online stores to buy their favourite phone accessories and PDA accessories. To begin with, online stores offer a safe, secure and fast way to buy mobile phone accessories and PDA accessories online. The consumers from the product gallery as per their own choice and from the comfort of their home at the click of a mouse! Moreover, many eCommerce sites also offer great discounts on their cell phones accessories and PDA accessories to their buyers. Buying your favourite mobile accessories on their Internet is really fast and easy. You have to log on to your favourite website, search for your favourite items, choose the product of your interest and then pay online through credit card or debit cards. Usually, it is the discounts on mobile accessories and PDA accessories that attract a number of people. Some websites offer you discounts if you enter a discount code while purchasing a mobile accessories and PDA accessories.
While so many online stores offer your favourite mobile phones accessories and PDA accessories, often choosing the right store becomes a real challenge to you. Hence, before buying your favourite mobile accessories and PDA accessories you should:
? Consider the prices of several online stores selling cell phones and PDA accessories.
? Check the payment options-whether they have flexible payment option.
? See how fast they can deliver your favourite mobile accessories.
? Consider the safety and security of the payment options.
? See if the online store is offering great discounts on their cell phones accessories and PDA accessories.
I gets lots of questions about people who want to know how I organize my accessories (Necklace wise) So since I moved to a new house I thought I should do a tutorial on how I hang them. I hope this is helpful if your accessories are tied in a knot. Follow Me on Twitter twitter.com What You need: 1. Your Necklaces 
2 Thumb Tacks/Nails ( make sure they are thin) you dont want to ruin your walls 3. A plain wall or space to hang them Its very simple and It a great way to decorate your walls.
Video Rating: 4 / 5
More Accessories Articles
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Consumer confidence slipped in June
In this June 13, 2012 photo, job seekers have their resumes reviewed at a job fair expo in Anaheim, Calif. More Americans sought unemployment aid last week, suggesting hiring remains sluggish. The Labor Department said Thursday June 14, 2012 that weekly unemployment benefit applications rose 6,000 to a seasonally adjusted 386,000, an increase from an upwardly revised 380,000 the previous week. (AP Photo/Jae C. Hong)
In this June 13, 2012 photo, job seekers have their resumes reviewed at a job fair expo in Anaheim, Calif. More Americans sought unemployment aid last week, suggesting hiring remains sluggish. The Labor Department said Thursday June 14, 2012 that weekly unemployment benefit applications rose 6,000 to a seasonally adjusted 386,000, an increase from an upwardly revised 380,000 the previous week. (AP Photo/Jae C. Hong)
In this June 19, 2012,photo, a shopper is reflected in a microwave oven on display on a showroom floor at Lowe's store in Atlanta. Consumer confidence fell in June for the fourth month in a row as lingering worries about the economy outweighed relief at the gas pump, according to a private research group. (AP Photo/David Goldman)
NEW YORK (AP) ? Americans can't seem to shake their uneasy feeling about the economy.
Consumer confidence fell in June for the fourth straight month as worries about jobs and the overall economy outweighed relief at the gas pump and an improvement in the housing market, according to a private research group.
The decline was modest; the Conference Board said Tuesday that its Consumer Confidence Index fell from 64.4 in May to 62 in June. But the four-month slide from 71.6 in February is significant and corresponds with a slowdown in hiring by U.S. companies over the same period.
The index is widely watched because consumer spending accounts for 70 percent of U.S. economic activity. A reading of 90 indicates a healthy economy. The index hit an all-time low of 25.3 in February 2009.
The latest survey shows that despite lower gas prices, Americans are still worried about stagnant hiring, low home values, the choppy stock market and a worsening European economy that some fear will hurt the U.S.
"We're trying to break free from this orbit, and we haven't been able to," said Mark Vitner, senior economist at Wells Fargo Economics. "Job market concerns will always trump swings in energy prices."
Alyson Seligman, who lives in Palm Beach Gardens, Fla., agrees. Seligman, who runs a small public relations firm, said lower gas prices haven't caused her to feel much more confident in the economy.
"Anything can turn on a dime," she said. "You have to be prepared."
Worries about job and income growth weighed the heaviest on Americans in the index, which was based on a survey conducted from June 1 through June 14 of about 500 randomly selected people nationwide. The margin of error for the index is plus or minus 5.5 points.
Those stating jobs are "hard to get" increased slightly to 41.5 percent from 40.9 percent, while those expecting more jobs in the months ahead declined to 14.1 percent from 15.4 percent. The proportion of consumers expecting an increase in their incomes declined to 14.8 percent from 15.7 percent.
Consumers' dwindling confidence since February corresponds with a sharp slowdown in hiring. Hiring averaged 96,000 during the combined period of March, April and May. That marked a slowdown from the average of 252,000 a month in the prior three months.
The strong hiring during the winter helped lift the Consumer Confidence Index from 40.9 in October to the highest reading it had been in a year during February. But in the following months that hiring has slipped, so has consumer confidence.
Meanwhile, a measure of the number of people applying for unemployment benefits over the past month has reached a six-month high, the government said last week. That suggests June could be another lackluster month for hiring. The government releases June data on July 6.
Americans also are grappling with declines in their retirement funds. After rallying earlier in the year, the stock market has lost its steam since the beginning of May amid concerns about the economy both here and abroad. The Dow Jones Industrial Average has fallen nearly 6 percent since early May.
On the news of declining consumer confidence, major stock indexes drifted between slight gains and losses on Tuesday, following steep losses the day before.
Still, Americans have some reasons to be optimistic. A widely watched home price index, released Tuesday, showed that home prices rose in nearly all major U.S. cities in April. That's the second straight month that prices in The Standard & Poor's/Case-Shiller home price index have increased in a majority of U.S. cities.
Additionally, gasoline prices have fallen sharply from a peak of $3.94 in early April to a national average of $3.40 per gallon Tuesday, according to auto club AAA, Wright Express and the Oil Price Information Service. And experts say gas could fall another 11 cents by July 4.
Despite those two positives, Americans are cautious about spending. Several companies, from restaurants to home goods sellers, have said recently that customers are pulling back on spending unless they are lured into stores by big discounts.
Bed Bath and Beyond last week forecast lower earnings for its current fiscal quarter that started in late May and said it needed to use more coupons to get people to spend. Furniture chain Ethan Allen Inc. said customer traffic is slowing and shoppers are taking more time to make purchasing decisions.
And Darden Restaurants Inc., which operates Olive Garden and Red Lobster restaurants, expects earnings that are short of Wall Street expectations and said customers were turned off by a $1 increase for Red Lobster's dish "Festival of Shrimp."
Given growing uncertainty about the economy, Michael P. Niemira, chief economist at The International Council of Shopping Centers trade group, on Tuesday trimmed his sales forecast for June by a 0.5 percentage point.
He now expects revenue at stores opened at least a year to be up 3 percent to 3.5 percent. That follows a 4 percent rise in May.
____
AP Economics Writer Chris Rugaber contributed to this report in Washington.
Follow Anne D'Innocenzio at http://twitter.com/ADInnocenzio
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Tuesday, June 26, 2012
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And the best benefit of using HTML5 for designer solutions is that with HTML5 you can effortlessly embed audio and video with your website without the necessitate of third party plug-ins such as flash. So Hire html5 designer and stay assured to get a professional and eye pleasing HTML5 website design.?
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No Name Farm/Ranch: Future Telling
Out of morbid curiosity I peaked back at some one year old blog posts, not quite sure what I'd find, but certain it would bring back all kinds of disgusting memories of the loan-getting/builder-interviewing/life-upside-downing process.
I found some of that, to be sure.? But then I also found this - so absolutely prescient that I shivered.? Especially to realize that exactly one year later - to the day - we brought home another year's worth of hay.? I shook the feeling off fast and went out to pet my snoozing pyrenees and feed the baby goats who (like last year's post says) weren't even born at the time I wrote it.? I guess it wasn't future-telling so much as just making sure things actually happened.?
Damn it feels good, either way.
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Monday, June 25, 2012
Tension as Egyptians wait for word of new president
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Learn to play piano in your sleep
Not really, but hearing known songs during a snooze may help people play them later
Web edition : Sunday, June 24th, 2012
A dreamland ditty played softly during a nap helps people hit the right notes while awake. Soft tones during sleep creep into the napping brain and strengthen playing skills, researchers report online June 24 in Nature Neuroscience.
The results don?t mean that after a nighttime Beethoven sonata, a piano novice will wake up with the ability to play it. But the results do suggest that an existing skill can be sharpened during a nap, says study coauthor Ken Paller of Northwestern University in Evanston, Ill.?
Earlier work by Paller and others has found that sound and odor cues during sleep can improve a person?s memory for the locations of objects. The new study extends those results by showing that a learned skill ? in this instance, playing music ? can also be influenced during sleep. ?Although these sorts of experiments are just getting started, ?the door is wide open,? Paller says. Musical ability, athletic prowess and other talents that normally require a lot of practice may be amenable to boosts during sleep.
Before the easy job of having a nap, 16 right-handed participants in the study had to do some actual work. Volunteers learned two different not-very-catchy tunes, played with their left hands on the a, s, d and f keys of a computer. In an arrangement similar to that of Guitar Hero, circles that floated up the screen told participants which key to hit and when.
After this training, the volunteers? chairs were converted into comfy beds for a 90-minute nap. When scalp electrodes indicated that the snoozers had entered slow-wave sleep, a phase that?s thought to be important for memory processing, researchers surreptitiously played one of the two songs the volunteers had just learned.
Refreshed from their siestas, volunteers were better overall at playing both songs than before their naps. But there was an important difference in this improvement: People were better at playing the song that was broadcasted during their nap than the song that hadn?t graced their sleep.
This effect may be caused in part by sleep spindles, waves of electrical activity that have been linked to memory processing during sleep. Spindles in the right premotor cortex ? the brain area that controls movement of the left hand ? were tied with the post-nap performance, the team found. ?The more spindles, the more benefit,? Paller says.
It?s not clear whether the gain represents a simple boost or just a bias in shifting the brain?s attention to one song at the expense of the other, Paller says. Sleep may offer a finite window of improvement, such that enhancing one skill may come at the expense of another.
Just because a skill can be sharpened during sleep doesn?t necessarily mean that it should, says sleep researcher Robert Stickgold of Harvard Medical School. ?I think your brain does a lot of triaging at night. Now, you?re trying to override that triaging and tell your brain what it should be worrying about.?
And overriding the brain is fraught with the problem of choosing what to listen to, Stickgold says. ?I would argue that sleep might be smarter than you.??
Found in: Body & Brain
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Sunday, June 24, 2012
Breast Cancer Survivor Fights To Swim Topless In Public Pool - The ...
When Jodi Jaecks, a breast cancer survivor who underwent a double mastectomy, decided she would try swimming in order to achieve the level of physical fitness she had before she started chemo, she ran into a bit of a problem ? there weren?t any swimsuits that fit her comfortably. Not one to be deterred, she ditched the idea of finding a comfortable suit and decided to swim topless instead.
But before that, when she found the tell-tale lump in her right breast, a photo of a?breast cancer survivor who had a double mastectomy ultimately led her to the decision to have both of her breasts removed:??It?s such a powerful image. She?s so healthy and fit. It showed me I could be in shape again. I could be happy again,? she said, citing the feeling of empowerment it gave her to undergo the mastectomy in lieu of removing the lump and waiting for the cancer to possibly resurface. Read more ?
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Settlement Could Cost Facebook Company Up to $103 Million in Revenue
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Create the Perfect Business Presentation with Whiteboard Mojo on ...
Vote! Excerpt from: Create the Perfect Business Presentation with Whiteboard Mojo on iPad
California based Viz Mojo Labs, Inc. today announces the upcoming release of Whiteboard Mojo for the iPad. A unique new business resource, this app was created to help tech savvy professionals, software developers & everyone in between implement visual aides & sketches for their presentations with e...
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Saturday, June 23, 2012
Giving to religious institutions drops for second year in a row. Why?
Giving to religious groups has slipped by a cumulative 3.7 percent since 2010. Still, religion remains America?s favorite charitable cause, with $95.88 billion in donations.
In this April photo, a man removes a section of stained glass from its frame during restoration at First United Methodist Church in Frankfort, Ky.
Hannah Reel/The State Journal/AP
EnlargeChurch congregations may need to pass the offering plate again because giving to religious institutions has dropped for the second year in a row.
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Charitable giving to the religious sector fell by 1.7 percent last year, according to the Giving USA 2012 report released this week. Since the start of 2010, giving to religious groups has slipped by a cumulative 3.7 percent (not adjusted for inflation).
This shows religion to be lagging in the evermore intense competition for donor dollars, even as other nonprofit sectors gain. Total charitable giving rose by 4 percent in 2011 to $298.4 billion. Of the eight sectors tracked by Giving USA, seven saw donations rise in both 2010 and 2011. Only religion lost ground.
Why is religion having a hard time?
?Declining attendance at religious services is part and parcel to the issue? of struggling to maintain or increase giving levels, says Robert Evans, a Philadelphia fundraising consultant for nonprofits and an author of the Giving USA 2012 report. ?If you have fewer people coming through the front door, then how do you do it??
But despite cutbacks in giving, religion remains America?s favorite charitable cause. With $95.88 billion in donations, faith-based organizations still collect far more than any other nonprofit segment. A distant second is education with $38.9 billion, followed by human services at $35.4 billion.
Yet religious institutions could be witnessing the start of a long-term slide, observers say. Precipitating factors, such as a weak economic recovery, portend more financial stress and hard choices about where institutions should cut in years ahead, according to David Roozen, director of the Hartford Institute for Religion Research at Hartford Seminary in Connecticut.
?The recession exacerbated downward pressure on church finances,? Mr. Roozen says. ?You?ll likely see a continuation of this? as unemployment and wage stagnation limit how much churchgoers can give.
Large congregations have fared best in the recession?s aftermath, Roozen says, as they consume a larger share of a shrinking pie. Slumping donations have translated into painful staff cuts for small congregations and denominational offices. In one telling sign, the United Methodist Church this year did away with its longstanding policy of guaranteeing appointments for clergy as churches come to rely on fewer pastors and part-timers for ministry.
Shrinking attendance isn?t all that?s hampered the faithful?s fundraising efforts, according to Mr. Evans. Religious institutions have largely failed to keep pace with other types of organizations, such as colleges and hospitals, in deploying professional development teams. Synagogues that employ professional fundraisers have found the investment pays off, Evans says, but most congregations have no one trained in the art of asking for money.
?There?s no donor fatigue,? says Evans, who is managing director of EHL Consulting Group. ?But houses of worship ... need to fine-tune their message more strongly for the people who want to make this a better country.?
What?s more, religious institutions are exempt from financial disclosure requirements that bind other nonprofits. As donors become more discreet and sophisticated, Evans says, they?ve come to expect more transparency than religious bodies are used to supplying. Donors who value transparency might therefore respond more favorably to nonreligious appeals.
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Video: Home Prices: What Gives?
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Friday, June 22, 2012
Schilling: Company crash cost me baseball fortune
FILE - In this Wednesday, May 16, 2012, file photo, former Boston Red Sox pitcher Curt Schilling, center, is followed by members of the media as he departs the Rhode Island Economic Development Corporation headquarters, in Providence, R.I. Schilling says the collapse of his 38 Studios video game company has probably cost him his entire baseball fortune, and he put part of the blame on Rhode Island Gov. Lincoln Chafee. Schilling said during an interview on WEEI-FM in Providence Friday, June 22, 2012, that he put more than $50 million of his own money in the company and that the money he made playing baseball is ?probably all gone.? (AP Photo/Steven Senne, File)
FILE - In this Wednesday, May 16, 2012, file photo, former Boston Red Sox pitcher Curt Schilling, center, is followed by members of the media as he departs the Rhode Island Economic Development Corporation headquarters, in Providence, R.I. Schilling says the collapse of his 38 Studios video game company has probably cost him his entire baseball fortune, and he put part of the blame on Rhode Island Gov. Lincoln Chafee. Schilling said during an interview on WEEI-FM in Providence Friday, June 22, 2012, that he put more than $50 million of his own money in the company and that the money he made playing baseball is ?probably all gone.? (AP Photo/Steven Senne, File)
PROVIDENCE, R.I. (AP) ? Former Boston Red Sox pitcher Curt Schilling said Friday that the collapse of his 38 Studios video game company has probably cost him his entire baseball fortune, and he placed part of the blame on Rhode Island officials, including Gov. Lincoln Chafee.
Schilling said during a 90-minute interview on WEEI-FM in Boston that he put more than $50 million of his own money in the company and that he's had to tell his family that "the money I saved during baseball was probably all gone."
Schilling said he hopes to return to work soon as an analyst for ESPN. He took a leave of absence from the network after 38 Studios filed for bankruptcy protection on June 7. The firm was lured to Providence from Massachusetts in 2010 after Rhode Island offered a $75 million loan guarantee. The state is working to determine how much it's on the hook for after the company's collapse.
While he conceded that he "absolutely" was part of the reason the company failed, he said public comments made by Chafee last month questioning the firm's solvency were harmful as the firm tried ? but failed ? to raise private capital to stay afloat.
"I think he had an agenda," Schilling said about Chafee.
Chafee vocally opposed the state's loan guarantee to 38 Studios when he was running for governor in 2010. But after it was a done deal, he was the company's "biggest cheerleader," Chafee spokeswoman Christine Hunsinger said Friday. She had no other immediate comments on Schilling's interview.
Schilling also accused Chafee of failing to work with an investor who was willing to put $15 million to $20 million into the company to help it succeed. He said the investor walked away because of Chafee's inaction.
38 Studios laid off its entire workforce ? nearly 300 employees in Providence and more in Maryland ? last month. That move came after it was more than two weeks late on a $1.1 million payment to the state; officials have said that was the first indication the company was in financial trouble.
The firm had sought millions of dollars in tax credits from Rhode Island as it struggled to stay afloat, but Schilling said Friday that he wasn't looking for a bailout.
State and federal authorities, meanwhile, are investigating 38 Studios' finances. Citizens Bank also has sued Schilling to recover $2.4 million in loans it made to 38 Studios.
Schilling, who also pitched for Baltimore, Houston, Philadelphia and Arizona, won the World Series three times and is perhaps best remembered for pitching Game 6 of the 2004 American League Championship Series with an injured ankle that stained his sock with blood.
Schilling said he hasn't done anything wrong. He said he never took any money from the company, not even a salary. He said the company was close to succeeding but just couldn't raise enough private capital. He also said he never intended to hurt the firm's workers.
"It's been kind of a surreal 60 days or 65 days," Schilling said. "It's crushing and devastating to see it fail the way it did."
Schilling was asked how the company's collapse has affected him personally.
"I don't know. ... It's not over yet," he said. "I would imagine the next foreseeable time in our lives is going to be consumed by this. It's a life-changing thing."
But he added, "I'm not asking for sympathy. It was my choice."
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SwiftKey 3 for Android out of beta: smarter auto spacing, $1.99 today (video)
"Lleasexqllme." SwiftKey 3 won't see that as gibberish, but as "Please call me," thanks to its new spacing prediction that has been repeatedly tweaked since the beta first came out in April. The final version is now available at the Google Play link below with a temporary half-price offer. It also promises a bigger space bar, a dedicated comma key, new themes, smarter punctuation and special character prediction, support for Android backup so you'll never lose the database of learned phrases, and overall less teeth-clenching while you're typing.
Continue reading SwiftKey 3 for Android out of beta: smarter auto spacing, $1.99 today (video)
SwiftKey 3 for Android out of beta: smarter auto spacing, $1.99 today (video) originally appeared on Engadget on Thu, 21 Jun 2012 03:01:00 EDT. Please see our terms for use of feeds.
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Thursday, June 21, 2012
Do Zero Calorie Sports Drinks Work? | Davey Wavey Fitness
Athletes and avid exercisers often reach for sports drinks as a way to replenish and hydrate their bodies. To tap into new markets, most of the top brands ? including Powerade and Gatorade ? have low-calorie or even no-calorie product extensions.
But do these products actually work? Are they effective? Or is it just a marketing gimmick?
The answer is yes. They do work ? to some degree. But it?s also a marketing gimmick.
When we sweat, we tend to lose electrolytes. If your balance of electrolytes is off, you may experience weakness, twitching, fatigue, confusion or a handful of other hindering issues. Just like traditional sports drinks, the low or no-calorie alternatives contain the electrolytes your body needs during intense exercise. The resulting electrolyte balance can help athletes maximize their performance levels.
But if you?re looking for a low or no-calorie sports drink to boost your energy levels or restore depleted glycogen, think again. Very literally, we measure energy in calories. And by definition, a zero calorie sports drink contains zero energy. For this reason, there?s really something ridiculous about the trend towards reduced calorie sports beverages.
Moreover, our bodies need carbohydrates after exercise. If we don?t consume carbs through the food we eat or the beverages we drink, our bodies can breakdown hard-earned muscle to get the glycogen that?s needed. And low or no-calorie sports drinks, which often have little or no carbohydrates, won?t give your body the fuel it needs.
In my opinion, low or no-calorie beverages don?t deserve the label ?sports drinks.? In fact, I think the marketing can be misleading for consumers. While these low or no-calorie options provide some benefits, traditional sports drinks ? or even coconut water ? are a much smarter choice.
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New candidate drug stops cancer cells, regenerates nerve cells
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 21-Jun-2012[ | E-mail |
Share ] Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center
CINCINNATI Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites.
Researchers from Cincinnati Children's Hospital Medical Center report their findings online June 21 in Chemistry & Biology. The scientists named their lead drug candidate "Rhosin" and hope future testing shows it to be promising for the treatment of various cancers or nervous system damage.
The inhibitor overcomes a number of previous scientific challenges by precisely targeting a single component of a cell signaling protein complex called Rho GTPases. This complex regulates cell movement and growth throughout the body. Miscues in Rho GTPase processes are also widely implicated in human diseases, including various cancers and neurologic disorders.
"Although still years from clinical development, in principle Rhosin could be useful in therapy for many kinds of cancer or possibly neuron and spinal cord regeneration," said Yi Zheng, PhD, lead investigator and director of Experimental Hematology and Cancer Biology at Cincinnati Children's. "We've performed in silica (computerized) rational drug design, pharmacological characterization and cell tests in the laboratory, and we are now starting to work with mouse models."
Because the role of Rho GTPases in cellular processes and cancer formation is well established, researchers have spent years trying to identify safe and effective therapeutic targets for specific parts of the protein complex. In particular, scientists have focused on the center protein in the complex called RhoA, which is essential for the signaling function of the complex. In breast cancer for example, increased RhoA activity makes the cancer cells more invasive and causes them to spread, while a deficiency of RhoA suppresses cancer growth and progression.
Despite this knowledge, past efforts to develop an effective small-molecule inhibitor for RhoA have failed, explained Zheng, who has studied Rho GTPases for over two decades. Most roadblocks stem from a lack of specificity in how researchers have been able to target RhoA, a resulting lack of efficiency in affecting molecular processes, problems with toxicity, and the inability to find a workable drug design.
For the current study, Zheng and his colleagues started with the extensive body of research from Cincinnati Children's and other institutions describing the processes and functions of Rho GTPases. They then used high-throughput computerized molecular screening and computerized drug design to reveal a druggable target site. This also provided a preliminary virtual simulation on the potential effectiveness of candidate drugs.
A key challenge to binding a small-molecule inhibitor to RhoA is the protein's globular structure and lack of surface pocket areas suitable for easy binding, Zheng said. The unique chemical structure of the lead compound identified by researchers, Rhosin, allows it to effectively bind to two shallow surface grooves on RhoA. This enables the candidate drug to take root and begin affecting cells. The two-legged configuration of Rosin also describes a useful drug design strategy for more effectively targeting difficult molecular sites like RhoA.
The researchers also wanted to make sure Rhosin effectively blocked what are known as guanine nucleotide exchange factors (GEFs). Guanine nucleotide is a critical energy source and signaling component of cells. Activation of GEFs is required to set off the regulatory signaling of GTPases (GTP stands for guanosine triphosphate).
After conducting a series of laboratory cell tests to verify the targeting and binding capabilities of Rhosin to RhoA, the researchers then tested the candidate drug's impact on cultured breast cancer cells and nerve cells.
In tests on a human breast cancer cells, Rhosin inhibited cell growth and the formation of mammary spheres in a dose dependent manner, acting specifically on RhoA molecular targets without disrupting other critical cellular processes. Rhosin does not affect non-cancerous breast cells. This, along with other tests the scientists performed, indicated Rhosin's effectiveness in targeting RhoA-mediated breast cancer proliferation, according to the researchers.
Researchers also treated an extensively tested line of neuronal cells with Rhosin, along with nerve growth factor, a protein that is important to the growth and survival of neurons. Rhosin worked with nerve growth factor in a dose-dependent way to promote the proliferation of branching neurites from the neuronal cells. Neurites are young or early stage extensions from neurons required for neuronal communications.
###
Funding for the study came from National Institutes of Health.
Also collaborating on the study were NanoTemper Technologies in Munich, Germany and the Drug Discovery Center at the University of Cincinnati.
About Cincinnati Children's:
Cincinnati Children's Hospital Medical Center ranks third in the nation among all Honor Roll hospitals in U.S. News and World Report's 2012 Best Children's Hospitals ranking. It is ranked #1 for neonatology and in the top 10 for all pediatric specialties. Cincinnati Children's is one of the top two recipients of pediatric research grants from the National Institutes of Health. It is internationally recognized for improving child health and transforming delivery of care through fully integrated, globally recognized research, education and innovation. Additional information can be found at www.cincinnatichildrens.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 21-Jun-2012[ | E-mail |
Share ] Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center
CINCINNATI Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites.
Researchers from Cincinnati Children's Hospital Medical Center report their findings online June 21 in Chemistry & Biology. The scientists named their lead drug candidate "Rhosin" and hope future testing shows it to be promising for the treatment of various cancers or nervous system damage.
The inhibitor overcomes a number of previous scientific challenges by precisely targeting a single component of a cell signaling protein complex called Rho GTPases. This complex regulates cell movement and growth throughout the body. Miscues in Rho GTPase processes are also widely implicated in human diseases, including various cancers and neurologic disorders.
"Although still years from clinical development, in principle Rhosin could be useful in therapy for many kinds of cancer or possibly neuron and spinal cord regeneration," said Yi Zheng, PhD, lead investigator and director of Experimental Hematology and Cancer Biology at Cincinnati Children's. "We've performed in silica (computerized) rational drug design, pharmacological characterization and cell tests in the laboratory, and we are now starting to work with mouse models."
Because the role of Rho GTPases in cellular processes and cancer formation is well established, researchers have spent years trying to identify safe and effective therapeutic targets for specific parts of the protein complex. In particular, scientists have focused on the center protein in the complex called RhoA, which is essential for the signaling function of the complex. In breast cancer for example, increased RhoA activity makes the cancer cells more invasive and causes them to spread, while a deficiency of RhoA suppresses cancer growth and progression.
Despite this knowledge, past efforts to develop an effective small-molecule inhibitor for RhoA have failed, explained Zheng, who has studied Rho GTPases for over two decades. Most roadblocks stem from a lack of specificity in how researchers have been able to target RhoA, a resulting lack of efficiency in affecting molecular processes, problems with toxicity, and the inability to find a workable drug design.
For the current study, Zheng and his colleagues started with the extensive body of research from Cincinnati Children's and other institutions describing the processes and functions of Rho GTPases. They then used high-throughput computerized molecular screening and computerized drug design to reveal a druggable target site. This also provided a preliminary virtual simulation on the potential effectiveness of candidate drugs.
A key challenge to binding a small-molecule inhibitor to RhoA is the protein's globular structure and lack of surface pocket areas suitable for easy binding, Zheng said. The unique chemical structure of the lead compound identified by researchers, Rhosin, allows it to effectively bind to two shallow surface grooves on RhoA. This enables the candidate drug to take root and begin affecting cells. The two-legged configuration of Rosin also describes a useful drug design strategy for more effectively targeting difficult molecular sites like RhoA.
The researchers also wanted to make sure Rhosin effectively blocked what are known as guanine nucleotide exchange factors (GEFs). Guanine nucleotide is a critical energy source and signaling component of cells. Activation of GEFs is required to set off the regulatory signaling of GTPases (GTP stands for guanosine triphosphate).
After conducting a series of laboratory cell tests to verify the targeting and binding capabilities of Rhosin to RhoA, the researchers then tested the candidate drug's impact on cultured breast cancer cells and nerve cells.
In tests on a human breast cancer cells, Rhosin inhibited cell growth and the formation of mammary spheres in a dose dependent manner, acting specifically on RhoA molecular targets without disrupting other critical cellular processes. Rhosin does not affect non-cancerous breast cells. This, along with other tests the scientists performed, indicated Rhosin's effectiveness in targeting RhoA-mediated breast cancer proliferation, according to the researchers.
Researchers also treated an extensively tested line of neuronal cells with Rhosin, along with nerve growth factor, a protein that is important to the growth and survival of neurons. Rhosin worked with nerve growth factor in a dose-dependent way to promote the proliferation of branching neurites from the neuronal cells. Neurites are young or early stage extensions from neurons required for neuronal communications.
###
Funding for the study came from National Institutes of Health.
Also collaborating on the study were NanoTemper Technologies in Munich, Germany and the Drug Discovery Center at the University of Cincinnati.
About Cincinnati Children's:
Cincinnati Children's Hospital Medical Center ranks third in the nation among all Honor Roll hospitals in U.S. News and World Report's 2012 Best Children's Hospitals ranking. It is ranked #1 for neonatology and in the top 10 for all pediatric specialties. Cincinnati Children's is one of the top two recipients of pediatric research grants from the National Institutes of Health. It is internationally recognized for improving child health and transforming delivery of care through fully integrated, globally recognized research, education and innovation. Additional information can be found at www.cincinnatichildrens.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Wednesday, June 20, 2012
Heart Attacks Can Trigger Post-Traumatic Stress - Health News ...
Getty Images
By Amanda MacMillan
WEDNESDAY, June 20, 2012 (Health.com) ? When people think of post-traumatic stress disorder (PTSD), they?re apt to picture combat veterans or the victims of violence and sexual assault. But new research suggests post-traumatic stress is also common following another kind of harrowing experience: heart attacks.
As many as 1 in 8 people who survive a heart attack will go on to develop symptoms of PTSD, a new analysis has found. And to make matters worse, PTSD symptoms appear to increase the risk of having a second heart attack or dying prematurely.
A heart attack, in which blood flow to the heart is suddenly interrupted, is a common?and sometimes terrifying?experience, says Donald Edmondson, PhD, the lead author of the analysis and an assistant professor of behavioral medicine at Columbia University Medical Center, in New York City.
?About 1.4 million people [in the United States] have heart attacks every year; that?s as many people as are in our entire active military,? Edmondson says. ?That feeling that your life is in danger?the loss of control when your body turns on you?is something that these people have a hard time forgetting.?
Previous research has found that heart attacks can contribute to depression, and a number of small studies have suggested a similar link to PTSD, a type of anxiety disorder. To assess just how common the disorder is in this population, Edmonson and his colleagues pooled and re-analyzed the results of 24 studies comprising 2,384 heart attack survivors from around the world.
Overall, 12% of study participants developed significant PTSD symptoms after having a heart attack, and 4% met the official criteria for a PTSD diagnosis. Although the methods varied from study to study, researchers generally focused on classic symptoms of the disorder, including frequent nightmares or flashbacks, intrusive thoughts, and elevated blood pressure or heart rate.
The findings, which appear this week in the journal PLoS ONE, are important for doctors and especially cardiologists, most of whom aren?t trained to look for signs of anxiety in heart patients, says Ramin Ebrahimi, MD, an interventional cardiologist and clinical professor of medicine at the University of California, Los Angeles.
?It has become hard for physicians to have a holistic approach and to consider the whole picture,? says Ebrahimi, who was not involved in the new analysis. ?As a cardiologist, my main focus is opening the artery and making sure the medication is appropriate. Most doctors aren?t thinking about whether the person is scared or traumatized at that point.?
Next page: Can PTSD make things worse?
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